11/2/15 |
Dr. Tomedi |
Answering a clinical question, evaluating evidence |
|
Answering a clinical question.ppsm |
11/16/15 |
Jared Lunkenheimer |
Topical NSAIDs
|
Consider in patient with muscle strain, especially in setting of contraindications for oral NSAIDs.
|
Cochrane Review- Topical NSAIDs.pdf |
11/30/15 |
Stephanie McGirt & Dr. Tomedi |
Evaluating the SPRINT trial |
More intensive blood pressure control (systolic < 120) may be appropriate for patients with increased cardiovascular risk |
SPRINT hypertension trial.pdf |
1/18/16 |
Andrew Russell and Dr. Tomedi |
HCTZ versus chlorthalidone |
Chlorthalidone is more effective at controlling blood pressure and preventing cardiovascular disease |
Chlorthalidone vs HCTZ-SR.pdf
HCTZ vs Chlorthalidone-SR.pdf
|
5/16/16 |
Molly McClain |
USPSTF recommendations for aspirin |
|
Aspirin for CVD and Cancer Prevention-USPSTF.pdf |
6/6/16 |
Tu Dao |
Hypertension goals in the elderly |
|
Intensive BP control in Elderly-RCT-2.pdf |
6/27/16 |
Jared Lunkenheimer |
Evidence for Mediterranean diet |
|
Mediterranean diet-secondary prevention.pdf
Mediterranean Diet and Breast Cancer- RCT.pdf
Mediterranean Diet and Age-Related Cognitive Decline-RCT.pdf
|
8/8/16 |
Phung Vo |
Aspirin for prevention of pre-eclampsia |
Start low dose aspirin (81mg) at 12 weeks for high risk patients |
https://www.acog.org/About-ACOG/News-Room/Practice-Advisories/Practice-Advisory-Low-Dose-Aspirin-and-Prevention-of-Preeclampsia-Updated-Recommendations
http://www.uspreventiveservicestaskforce.org/Page/Document/RecommendationStatementFinal/low-dose-aspirin-use-for-the-prevention-of-morbidity-and-mortality-from-preeclampsia-preventive-medication
|
8/22/16 |
Meredith Barlow |
Pharmacotherapy has limited evidence for use in insomnia (and carries risk) |
|
Pharmacologic Treatment of Insomnia-SR.pdf |
8/29/16 and 9/12/16 |
Phung Vo
and Jerica Johnson
|
CBT for insomnia (role of PCP and internet-based programs) |
Internet CBT is cost-effective and effective in both insomnia and PTSD |
Insomnia-Psychological and Behavioral Interventions-SR.pdf
Internet CBT-I- SR.pdf
Internet based CBT for PTSD.0-S0165032714001116-main copy.pdf
Internet based CBT for PTSD.0-S0165032714001116-main copy.pdf
|
9/26/16 |
Jared Lunkenheimer |
Prevention of recurrent nephrolithiasis in adults |
Increase fluid intake to produce > 2 liters of urine a day, no evidence for dietary modifications, low quality evidence for HCTZ (decrease calcium excretion) |
ACP Guidelines: Prevention of Recurrent Nephrolithiasis.pdf
|
10/10/16 |
Molly McClain |
Treatment of resistant depression |
|
Treatment-resistant depression-review article.pdf
Treatment of resistant depression-AHRQ review.pdf
Augmentation with atypical antipsychotics for depression-SR.pdf
|
10/31/16 |
Meredith Barlow |
Vitamin D for prevention of osteoporosis |
|
Discussion about calcium supplementation and CVD risk: Calcium and Cardiovascular Disease- SR.pdf |
11/7/16 |
Sonja Halterman |
Efficacy of medication for treatment of obesity |
|
Long-term Drug Treatment of Obesity-JAMA.pdf |
11/14/16 |
Rania Khan |
Brief intervention for obesity |
|
Obesity screening and treatment in primary care-RCT.pdf |
11/28/16 |
Phung Vo |
USPSTF recommendations for primary prevention of CVD |
USPSTF recommends using low-moderate dose statins in adults age 40-75 with 1 or more CVD risk factors AND an ASCVD risk of 10% or greater.
|
Statins for Primary Prevention of CVD- USPSTF.pdf
|
1/9/17 |
Michelle Chungtuyco |
Prophylaxis of migraines |
Melatonin is as good as amitryptilline and better than placebo in terms of decrease in migraine-headache days per month.
|
Migraine RCT.pdf |
1/16/17 |
Sarah Friedberg |
NSAIDs for treatment of dysmenorrhea |
NSAIDs are more effective than placebo (consider naproxen) |
NSAIDs for dysmenorrhea.pdf |
1/23/17 |
Trisha Fleet |
Monitoring of CBG by patients not on insulin |
Limited effect for self monitoring of blood glucose when not on insulin at 6 months and effect subsides by 12 months |
Self-monitoring of blood glucose - Cochrane SR.pdf |
2/13/17 |
Andy Russell |
Treatment for overactive bladder |
Anticholinergic drugs are effective for treatment of OAB and tolterodine might be preferred over oxybutynin for reduced risk of dry mouth. |
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD003193.pub4/full
http://onlinelibrary.wiley.com/doi/10.1002/14651858.CD005429.pub2/full
|
2/20/17 |
Meredith Barlow |
NSAIDs for pain and bleeding due to IUD. |
NSAIDs reduce pain and bleeding associated with IUD use. |
NSAIDs for pain & cramping with IUDs.pdf |
2/27/17 |
Jerica Johnson
|
Subclinical hypothyroidism |
There is no evidence for thyroid replacement in those with TSH <10 and normal T3/T4. There is greater risk of CAD in those with TSH>10. |
Subclinical Hypothyroidism.pdf
Subclinical hypothyroidism increased risk of CAD.pdf
Subclinical Hypothyroidism: Monday Clinic Teaching.gdoc
|
3/13/17 |
Sarah Friedberg |
Buprenorphine for opiate use disorder |
Fixed medium-high doses of buprenorphine were equivalent to methadone |
Buprenorphine or methadone for OUD- Cochrane review.pdf
Buprenorphine for heroin dependence-Sweden 2003 RCT.pdf
|
3/20/17 |
Rania Khan |
Discontinuation of statin therapy |
National guidelines support the lack of CV risk reduction
benefit in patients with CKD receiving dialysis, HFrEF, and patients greater than 75 years of age without known ASCVD
|
discontinuation of statins.pdf |
4/3/17 |
Michelle Chungtuyco |
Metformin in patients with CKD |
Can use metformin in patients with GFR > 30 without increasing risk of lactic acidosis (if kidney function is stable) |
Metformin and CKD.pdf
Metformin Commentary.pdf
|
4/24/17 |
Phung Vo |
NSAIDs for knee and hip osteoarthritis |
Diclofenac is most effective for improving pain and function |
NSAIDs.pdf |
5/1/17 |
Tanya Reyes |
Vascular and upper GI effects of NSAIDs |
Naproxen is associated with less vascular risk than other NSAIDs |
NSAIDS Vascular and UGI effects- SR.pdf |
5/15/17 |
Stephanie Hubbard-McGirt |
Treatment for low back pain |
NSAIDs have small effect for acute and chronic back pain, nonpharmacologic therapies have greater effect |
Nonpharmacologic therapies for low back pain- SR.pdf
Pharmacologic therapies for low back pain- SR.pdf
|
7/3/17 |
Michelle Chungtuyco |
Vitamin D supplementation for prevention of mortality |
|
Vitamin D prevention of mortality.pdf |
7/10/17 |
Dr. Tomedi |
Selecting a clinical question and searching for articles |
|
Using Evidence for Patient Care July 2017.ppt |
7/17/17 |
Dr. Tomedi |
Evaluating the evidence |
|
Critical Appraisal-SYSTEMATIC REVIEW.docx
Critical appraisal of RCT.docx
|
7/24/17 |
Dr. Tomedi |
Beta-blockers for hypertension |
Beta-blockers should not be used as first line anti-hypertensive agents (not as effective at decreasing morbidity and mortality as other classes). Carvedilol is not more effective at lowering BP than other beta-blockers. |
Beta-blockers for hypertension.pdf |
7/31/17 |
Phung Vo |
Target for diabetes control |
Tighter diabetes control (HgbA1c < 7) is not associated with significant benefits and there may be risks. |
Glucose targets for preventing DM complications-Cochrane SR.pdf |
8/7/17 |
Sarah Friedberg |
Risk of GI bleeding with DOACs |
Apixaban caused less GI bleeds than rivaroxaban or dabigatran |
DOACs and GI bleed.pdf |
8/14/17 |
Steven Nguyen
|
Triamcinolone vs. saline joint injections |
Among patients with symptomatic knee osteoarthritis, intra-articular triamcinolone, compared with intra-articular saline, increased cartilage volume loss and had no effect on knee pain over 2 years. |
Intra-articular steroid injections.pptx
Intra-articular triamcinolone vs. Saline.pdf
|
9/11/17 |
Phung Vo |
Low dose CT scan screening for lung cancer |
Screen all pts ages from 55-80 who currently smoke with a 30pk year hx or have quit <15yrs ago annual with low dose CT to decrease mortality from lung cancer. |
lung cancer screening.pdf |
9/18/17 |
Rania Khan |
Steroids versus NSAIDs for acute gout flares |
Not enough data to support steroids as first line therapy for acute gout flares - however consider in patients with comorbidities like CKD, in which NSAIDs would not be safe. |
Steroids vs NSAIDs for acute gout-RCT.pdf |
10/16/17 |
Zainab Aldaoseri |
Vision screening in preschool age children |
Studies were limited and do not establish whether screening is effective |
Vision Screening article-JAMA.pdf |
10/23/17 |
Brynne Latterell |
Vitamin D supplementation in asthmatics |
Vitamin D supplementation decreased the rate of asthma exacerbations requiring systemic corticosteroids |
Vit D for asthma-SR.pdf |
10/30/17 |
Sarah Friedberg |
Validated measures for depression screening in Vietnamese population |
|
Depession Measures Among Vietnamese- SR.pdf |
11/20/17 |
Phung Vo |
Hypertension Guidelines 2017 |
Treat if BP > 130/80 and 10 year ASCVD risk > 10% (or known CVD). Otherwise treat if BP > 140/90. Goal for treatment is 130/80. |
Hypertension Guideline 2017.pdf |
12/4/17 |
Michelle Chungtuyco |
Starting contraception/pregnancy test |
|
QuickstartAlgorithm.pdf |
12/11/17 |
Addison Himmelberger |
Resource guide for integrative approaches to chronic pain |
|
Alternative Medicine Options in the Community.docx |
12/18/17 |
Camilo Werlin-Martinez |
Association of PAP with cardiovascular outcomes |
The use of PAP was not associated with reduced risk of cardiovascular outcomes (did improve sleepiness and sense of wellbeing) |
12:18:17 Teaching OSA.webloc
Association of PAP with cardiovascular events.pdf
PAP and CV outcomes- EBM review.pdf
|
1/22/18 |
Brynne Latterell |
Hormone replacement therapy for vasomotor symptoms of menopause |
Transdermal estradiol and protestogen were most effective at vasomotor symptom relief |
POEMs-menopausal symptoms.pdf
Sarri_et_al-2017-BJOG__An_International_Journal_of_Obstetrics_&_Gynaecology.pdf
HRT on cardiovascular outcomes.pdf
|
1/29/18 |
Zainab Aldaoseri |
Statins for primary prevention of cardiovascular disease |
USPSTF recommends statin for patients age 40-75 with 1 or more CVD risk factors and 10 year ASCVD risk > 10% |
Statins for Primary Prevention of CVD- USPSTF.pdf
Statins for Prevention of CVD in Adults- JAMA.pdf
|
2/12/18 |
Dr. Tomedi |
USPSTF app for phone: AHRP ePSS |
Review of USPSTF guidelines with levels of evidence |
https://itunes.apple.com/us/app/ahrq-epss/id311852560?mt=8 |
2/19/18 |
Jerica Johnson |
2017 ACC/AHA Guidelines for Management of Hypertension |
Guidelines state treat BP > 130/80 in patients with 10 year ASCVD risk > 10% |
|
3/5/18 |
Phung Vo |
Reviewed guidelines for diagnosis and management of GDM |
Screen with 1 hour GTT (cut off at UNM is 135). If positive, do 3 hour GTT. If 2 abnormal values, patient has GDMA1, refer to MFM Diabetes Educator and have patient check fasting and 2 hour PP sugars. If CBGs are > 95 fasting or 120 2 hours PP, consider starting medication. |
ACOG Bulletin on GDM |
3/12/18 |
Steven Nguyen |
Injectable Naltrexone vs. Daily Buprenorphine-Naloxone |
Extended release Naltrexone was as effective as buprenorphine-naloxone for short term abstinence from heroin |
Naltrexone.Injectable.pdf |
3/26/18 |
Sarah Friedberg |
Treatment of influenza |
Oseltamivir and zanamivir have small, non-specific effects on reducing the time to alleviation of influenza symptoms in adults |
Treatment of Flu.pdf |
4/2/18 |
Jaleh Akhavan |
Choice of antidepressants based on acceptability and efficacy |
Amitriptyline, escitalopram, mirtazapine, paroxetine, venlafaxine are more effective |
Antidepressants-network meta-analysis.pdf
Picking the optimal antidepressant-commentary.pdf
|
4/16/18 |
Elena Gandera |
Opioid vs nonopioid medications for chronic pain |
Non-opioid treatment was associated with significantly better pain control at 12 months compared
to opioids.
|
opioids vs nonopioids for pain- SPACE RCT.pdf
SPACE Trial.pptx
|
4/23/18 |
Camilo Werlin-Martinez |
Non-invasive tests for H. pylori |
Urea breath tests have high diagnostic accuracy for H. pylori (better than serology or stool antigen). Test is no longer available at UNM. |
non-invasive tests for H.pylori.pdf |
5/21/18 |
Rania Khan |
Alcohol use disorder in primary care |
Medical management with naltrexone, alone or with CBI, was most successful |
COMBINE study-RCT.pdf
AUD in the Primary Care Setting.pdf
Medical Management session guide.pdf
|
6/4/18 |
Hieu Nguyen |
PSA for detection of prostate cancer |
PSA may reduce prostate cancer mortality risk but is associated with false-positive results, biopsy complications, and over diagnosis. |
Screening for Prostate Cancer-USPSTF SR.pdf |
6/25/18 |
Jerica Johnson |
Sertraline in patients with CKD |
In non-dialysis dependent CKD and MDD, sertraline did not significantly improve depressive symptoms compared to placebo |
sertraline in CKD.pdf |
7/30/18 |
Dr. Tomedi
|
Intro to EBM |
|
SEHC noon presentation re EBM (1).ppt |
8/6/18 |
Steven Nguyen |
Information Mastery and JAMA Int Med article on repeat BP measurement |
Repeat BP measurement showed a decrease in systolic BP of 8mmHg. This resulted in increased HTN control rate from 61% to 73%. |
Clinic Educaton - Info Master & BP Repeat.pptx
nihms981217-2.pdf
|
8/13/18 |
Hieu Nguyen |
Melatonin for migraine prevention |
Melatonin 3mg is as effective as amitriptyline, but with fewer side effects |
Melatonin for migraine prevention.pdf |
9/10/18 |
Stacy Nguy |
USPSTF updated guidelines for cervical cancer screening |
Screen women age 30 to 65 with cytology every 3 years, HPV testing every 5 years, or cotesting every 5 years. |
Screening for cervical cancer- USPSTF.pdf
Cervical cancer screening with HPV testing- SR for USPSTF.pdf
|
9/17/18 |
Rania Khan |
Macrobid versus fosfomycin for UTI |
In uncomplicated UTI in women, Macrobid was more effective than fosfomycin |
jama_Huttner_2018_oi_180034.pdf |
10/1/18 |
Ari Faber |
Tobacco cessation |
Quitting smoking abruptly is more likely to lead to lasting abstinence than cutting down first, even for smokers who initially prefer to quit by gradual reduction. |
http://annals.org/aim/article-abstract/2501853/gradual-versus-abrupt-smoking-cessation-randomized-controlled-noninferiority-trial# |
10/8/18 |
Rory Aufderheide |
Gabapentin for chronic low back pain |
While there is evidence to support gabapentinoids for neuropathic pain, this study found that there is little to support their use for chronic lower back pain, with overall more harm than benefit. |
Gabapentinoids for chronic low back pain.pdf |
10/29/18 |
Jaleh Akhavan |
LABAs for mild to moderate COPD |
Tiotropium (LABA) resulted in a higher FEV1 than placebo at 2 years in patients with COPD GOLD stage 1 or 2 |
Tiotropium in early-stage COPD- RCT.pdf
GOLD Pocket Guide 2018.pdf
|
11/5/18 |
Brynne Latterell |
Clinic versus ambulatory blood pressure measurements |
Ambulatory blood pressure measurements were a stronger predictor of all-cause mortality |
Clinic vs ambulatory BP monitoring.pdf |
11/26/18 |
Hieu Nguyen |
Zolendronate for osteopenia |
The current trial showed that treatment with Zoledronate every 18 months, with Vitamin D and minimal calcium supplements, reduced the risk of fragility fractures over the course of 6 years in older women with osteopenia. |
Zoledronate for Osteopenia- RCT.pdf |
12/10/18 |
Jillian Moore |
Melatonin for insomnia |
For people with primary sleep disorders, melatonin has clinically insignificant effects on sleep latency, total sleep duration, and sleep quality. |
melatonin 2012 PLOS.pdf |
1/7/19 |
Steven Nguyen |
Diabetes medications |
Among insured adult patients with type2 diabetes initiating second-line ADM therapy, the short-term cardiovascular outcomes of GLP-1 receptor agonists, SGLT-2 inhibitors, and DPP-4 inhibitors were similar. Higher cardiovascular risk was associated with use of sulfonylureas or basal insulin compared with newer ADM classes.
|
Antidiabetic medications and CVD events.pdf
Diabetes Medications.pdf
|
2/4/19 |
Sarah Friedberg |
Glucosamine for osteoarthritis |
|
Glucosamine.pptx |
2/11/19 |
Jaleh Akhavan |
NAFLD and hepatic steatosis |
Low free sugar diet improves hepatic steatosis in adolescent boys |
https://docs.google.com/presentation/d/1NKc8nuZ8IbR33EYt7Lt483Q3wxn3ZXYE9HKb867IDU4/edit?usp=sharing
effect of low sugar diet on NAFLD.pdf
|
3/18/19 |
Rory Aufderheide |
Duration of treatment for AOM in children age 6 - 23 months |
If you are going to treat AOM in 6-23 mos with Augmentin, the full 10 day course is better than a 5 day course because there are improved treatment outcomes and symptomatic improvement without increased side effects or harmful outcomes.
|
https://www.aafp.org/afp/2017/0401/p457.html
POEMs-Antibiotic duration for AOM.pdf
|
3/25/19 |
Brynne Latterell |
Water intake for prevention of recurrent UTI |
Increased water intake was effective for preventing recurrent UTI in premenopausal women at high risk for recurrence
|
Water Intake and UTI-RCT.pdf |
4/1/19 |
Zainab Aldaoseri |
Early allergen introduction for prevention of food allergies |
Early peanut or egg introduction into the infant diet was associated with lower risk of developing egg or peanut allergies. |
https://www.ncbi.nlm.nih.gov/m/pubmed/27654604/ |
4/22/19 |
Steven Nguyen |
Evidence for SLGT2 inhibitors for secondary prevention of cardiovascular disease |
SGLT2i have moderate benefits on atherosclerotic major adverse cardiovascular events that seem confined to patients with established atherosclerotic cardiovascular disease.
|
SGLT2 Inhibitors.SystematicReview.pdf |
4/29/19 |
Jillian Moore |
Omega-3 fatty acids for prevention of cardiovascular disease |
Omega-3 fatty acid (fish oil) supplements have little to no effect on all-cause mortality, cardiovascular mortality, or cardiovascular events. The fish oil supplement industry consumes millions of tons of marine wild life each year. |
Omega-3 fatty acids for prevention of CVD.pdf
Fish oil.pdf
|
5/6/19 |
Jaleh Akhavan and Dr. Tomedi |
Benefit of omega 3 fatty acids in pregnancy |
Preterm birth < 37 weeks and early preterm birth < 34 weeks were reduced in women receiving omega-3 long chain polyunsaturated fatty acids (LCPUFA) compared with no omega-3. There was a possibly reduced risk of perinatal death and of neonatal care admission and a reduced risk of LBW babies. Therefore a good case can be made for offering a 500 mg -1,000 mg supplement to pregnant women. |
Omega-3 fatty acids and pregnancy-Dec2018.ppt
Omega- fatty acids during pregnancy-Cochrane SR.pdf
|
5/20/19 |
Rania Khan |
Signs and Symptoms that Rule out Community Acquired Pneumonia in Outpatient Adults |
Otherwise healthy adults with an acute respiratory infection who have normal vital signs and a normal pulmonary examination are very unlikely to have CAP. |
CAP in outpatient adults.pdf |
6/3/19 |
Farinaz Khan |
ACE-I and risk of lung cancer |
In this population based cohort study, the use of ACEIs was associated with an increased risk of lung cancer. The association was particularly elevated among people using ACEIs for more than five years.
|
ACE-I risk of lung ca.pdf |
6/10/19 |
Chrys Djatche de Kamgaing |
Iron supplementation for heart failure |
Our meta-analysis suggests that iron therapy can reduce heart failure hospitalization, increase cardiac function, improve quality of life, and decrease serum levels of NT-proBNP and CRP in patients with heart failure.
|
Iron supplement for heart failure.pdf |
6/17/19 |
Jerica Johnson |
Triple therapy for patients with advanced COPD |
Use of triple therapy resulted in a lower rate of moderate or severe exacerbations of COPD, better lung function, and better health related quality of life than dual therapy or monotherapy in patients with advanced COPD.
|
triple therapy in management of COPD.pdf |
6/24/19 |
Stacy Nguy |
Aspirin for primary prevention in patients with diabetes |
Aspirin prevented major vascular events but benefits were counterbalanced by bleeding risk.
|
ASA and DM.pdf
ASCEND Study.pdf
|
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